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Sanyal, Arun J et al

Animal Model Evidence The systemic evidence base is entirely preclinical: Pulmonary fibrosis (mouse model): Intraperitoneal GHK-Cu at 0.2-20 micrograms/g/day protected against bleomycin-induced lung fibrosis by inhibiting TGF-beta1/Smad signaling and reducing oxidative stress (PMID 31809714)

The small intestinal epithelium is composed of villi that extend into the lumen and are lined by differentiated, post-mitotic cell types, and the crypts of Lieberkhn that contain Paneth cells and undifferentiated stem cells [16]